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Asymptomatic bacteriuria in pregnancy

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#1 Asymptomatic bacteriuria in pregnancy

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Asymptomatic bacteriuria in pregnancy

Asymptomatic bacteriuria is the significant presence of bacteria in the urine of an individual without symptoms. In pregnancy, the apparent reduction in Asymptomatic bacteriuria in pregnancy of pregnant bacyeriuria tends to encourage the growth of pathogens. This study was carried out to determine the prevalence of asymptomatic bacteriuria in pregnant women attending a primary health centre in Benin City, Nigeria. A total of 1, pregnant women were recruited for this study. All subjects were clinically identified to have no signs and symptoms of UTI. Clean catch midstream urine sample was collected from each patient into sterile universal bacterluria. The urine samples were examined microscopically Asyjptomatic by cultural method. Identification of isolates was by standard microbiological technique. A total of Escherichia coli was the most predominant organism followed closely by Staphylococcus aureus. Ciprofloxacin, Ceftriaxone and Augmentin were found to be the most effective antibiotics against the urinary isolates. Asymptomatic bacteriuria is not uncommon among antenatal patients in the population studied. Routine urine cultural test should be carried out on all antenatal patients in order pregnaancy identify any unsuspecting Asymptomatic bacteriuria in pregnancy. This measure will go a long way in reducing maternal and obstetric complications associated with pregnancy. Asymptomatic bacteriuria refers to the presence Asymptomatoc bacteria in urine. This is common during pregnancy. Asymptomatid apparent reduction in immunity of pregnant women appears to encourage the growth of both commensal and non-commensal microorganisms[ 2 ]. Pregnancy enhances the progression from asymptomatic to symptomatic Asymptomxtic which could lead to pyelonephritis and adverse Asymptomatic bacteriuria in pregnancy outcomes such as prematurity, low birth weight[ 5 ] and higher foetal mortality rates[ 67 ]. The adverse effects of undiagnosed asymptomatic bacteriuria on mother and child have made researchers to suggest routine culture screening for all pregnant women attending antenatal clinic[ 8 ] in order to...

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The current standard of practice is to treat pregnant patients with ASB with a 7-day course of oral antimicrobial agents. If bacteriuria persists women are retreated with the same of different agent for a second course of 7 to 14 days and they may be subsequently placed on prophylaxis. In nonpregnant women, an uncomplicated lower urinary tract infection may be treated with a short course regimen from 1 to 3 days. This approach has similar rates of persistent bacteriuria or symptoms following treatment when compared to women treated with a more conventional approach. If the infection recurs or persists, the patient may then be treated with the more traditional 7 to 14 day course. The advantages of single-dose regimens are cost and patient compliance, but a major disadvantage is the failure to eradicate uropathogens from the vaginal reservoir, which results in more frequent early recurrences. The three-day regimen is advocated to maintain the advantages of lower costs and patient compliance but improving cure rates. Multiple studies have shown the advantage of even a short course of antibiotics as opposed to no treatment. None Open Label Primary Purpose: Treatment Study Start Date: September Actual Primary Completion Date: January Actual Study Completion Date: Cephalexin Cephalexin will be prescribed for women with a positive urine culture but no symptoms of urinary tract infection. Nitrofurantoin Macrobid will be prescribed for women allergic to penicillin with a positive urine culture but no symptoms of urinary tract infection. Evidence that 3-day treatment is as effective as 7-day treatment of asymptomatic bacteriuria in pregnancy. Comparison of development of cystitis during pregnancy. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below....

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A common dilemma in clinical medicine is whether to treat asymptomatic patients who present with bacteria in their urine. There are few scenarios in which antibiotic treatment of asymptomatic bacteruria has been shown to improve patient outcomes. Because of increasing antimicrobial resistance, it is important not to treat patients with asymptomatic bacteriuria unless there is evidence of potential benefit. Women who are pregnant should be screened for asymptomatic bacteriuria in the first trimester and treated, if positive. Treating asymptomatic bacteriuria in patients with diabetes, older persons, patients with or without indwelling catheters, or patients with spinal cord injuries has not been found to improve outcomes. Urinary tract infections UTIs are one of the most common infections for which antibiotics are prescribed. The Infectious Diseases Society of America IDSA issued guidelines for the treatment of uncomplicated acute bacterial cystitis and acute pyelonephritis in women. The IDSA also has published guidelines on indications for the screening and treatment of asymptomatic bacteriuria in various patient populations. Pregnant women should be screened for asymptomatic bacteriuria in the first trimester of pregnancy. Pregnant women who have asymptomatic bacteriuria should be treated with antimicrobial therapy for three to seven days. Pyuria accompanying asymptomatic bacteriuria should not be treated with antimicrobial therapy. For information about the SORT evidence rating system, see page or https: Asymptomatic bacteriuria is common, with varying prevalence by age, sex, sexual activity, and the presence of genitourinary abnormalities Table 1 3 — 8. In healthy women, the prevalence of bacteriuria increases with age, from about 1 percent in females five to 14 years of age to more than 20 percent in women at least 80 years of age living in the community. Infecting organisms are diverse and include Enterobacteriaceae, Pseudomonas aeruginosa , Enterococcus species, and group B streptococcus. Organisms isolated in patients with...

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Asymptomatic bacteriuria is the presence of bacteria in a voided urine sample and is caused by bacterial colonization of the urinary tract. It affects about 5 to 10 percent of both sexually active and pregnant women. Asymptomatic bacteriuria is less prevalent in men. As the name indicates, asymptomatic bacteriuria does not cause symptoms. The condition simply refers to the detection of bacteria in a urine sample. Nonetheless, there is good reason to be concerned about this infection, particularly if you are pregnant, because it can lead to a symptomatic upper urinary tract infection namely, pyelonephritis , which can complicate pregnancy. Bacteria are typically introduced into the urinary tract during intercourse or when wiping after a bowel movement. Klebsiella pneumoniae, Proteus species, staphylococcal species, enterococci, and group B streptococci can also establish colonization. Because asymptomatic bacteriuria does not cause symptoms, it is important to know what increases your risk of infection. By being aware, you can help avoid the consequences of untreated asymptomatic bacteriuria by early detection and treatment. Researchers have identified a number of risk factors, which include:. If you have or might have any of these conditions, you are at risk for asymptomatic bacteriuria. You should talk to your doctor immediately. In non-pregnant women, asymptomatic bacteriuria rarely causes serious problems. However, in pregnant women this infection can progress upward, causing acute urethritis, acute cystitis, and acute pyelonephritis kidney infection. Pyelonephritis, in turn, can lead to adverse outcomes such as preterm labor, which is the most common cause of serious complications-including death-in newborn babies. A kidney infection can also lead to sepsis pathogenic organisms or toxins invading the blood or tissue and adult respiratory distress syndrome ARDS -both can be life threatening. Approximately 25 to 30 percent of asymptomatic bacteriuria cases in pregnancy will progress to symptomatic infection, three to...

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Oct 18, Author: Hormonal and mechanical changes can promote urinary stasis and vesicoureteral reflux. These changes, along with an already short urethra approximately cm in females and difficulty with hygiene due to a distended pregnant belly, help make UTIs among the most common bacterial infections during pregnancy. UTIs during pregnancy are associated with risks to both the fetus and the mother, including pyelonephritis , preterm birth, low birth weight, and increased perinatal mortality. In general, pregnant patients are considered immunocompromised UTI hosts because of the physiologic changes associated with pregnancy see Pathophysiology. These changes increase the risk of serious infectious complications from symptomatic and asymptomatic urinary infections even in healthy pregnant women. See Urinary Tract Infection in Females. Oral antibiotics are the treatment of choice for asymptomatic bacteriuria and cystitis. The standard course of treatment for pyelonephritis is hospital admission and intravenous antibiotics. Antibiotic prophylaxis is indicated in some cases see Treatment. Patients treated for symptomatic UTI during pregnancy should be continued on daily prophylactic antibiotics for the duration of their pregnancy. Although the condition-specific cost of asymptomatic bacteriuria or UTI in pregnancy is unknown, screening for these conditions in pregnant women is cost-effective, compared with treating UTI and pyelonephritis without screening. Goals for future research include targeting low-income groups and women in developing countries for screening and early treatment, as well as determining whether a causal relation exists between maternal UTI and childhood neurologic consequences. A diagnosis of UTI should be supported by a positive culture for a uropathogen, particularly in patients with vague symptoms. Acute cystitis involves only the lower urinary tract; it is characterized by inflammation of the bladder as a result of bacterial or nonbacterial causes eg, radiation or viral infection. Signs and symptoms include hematuria, dysuria, suprapubic discomfort, frequency, urgency, and nocturia. These symptoms are...

Asymptomatic bacteriuria in pregnancy

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Aug 7, - Antibiotic treatment can reduce the risk of kidney infections in pregnant women who have a urine infection but show no symptoms of infection. Asymptomatic bacteriuria occurs in 2% to 10% of pregnancies and, if not treated, up to 30% of mothers will develop acute pyelonephritis. This study was carried out to determine the prevalence of asymptomatic bacteriuria in pregnant women attending a primary health centre in Benin City, Nigeria.‎Introduction · ‎Patients and Methods · ‎Results. Panminerva Med. Dec;36(4) Asymptomatic bacteriuria in pregnancy: maternal and fetal complications. Grio R(1), Porpiglia M, Vetro E, Uligini R.

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